Hubungan Ketuban Pecah Dini dengan Kejadian Asfiksia Neonatorum di RSUD Panembahan Senopati Bantul Tahun 2026

Authors

  • Asri Novia Rahmawati Program Studi Diploma III Kebidanan, Politeknik Kesehatan Ummi Khasanah Bantul, Yogyakarta Author
  • Efi Trimuryani Program Studi Diploma III Kebidanan, Politeknik Kesehatan Ummi Khasanah Bantul, Yogyakarta Author
  • Eka Oktavia Program Studi Diploma III Kebidanan, Politeknik Kesehatan Ummi Khasanah Bantul, Yogyakarta Author

Keywords:

Premature Rupture of Membranes, Asphyxia, Neonatorum

Abstract

Neonatal asphyxia remains one of the leading causes of neonatal morbidity and mortality, both globally and nationally. Premature Rupture of Membranes (PROM) is thought to increase the risk of neonatal asphyxia through reduced amniotic fluid volume, umbilical cord compression, and impaired fetal oxygenation. Available data show that the infant mortality rate in Bantul Regency is among the highest in the Special Region of Yogyakarta, with neonatal asphyxia as one of the dominant causes, so further study of the relationship between these two conditions is needed. This study aimed to determine the relationship between premature rupture of membranes and the incidence of neonatal asphyxia at Panembahan Senopati Regional Hospital, Bantul, in 2026. This was a quantitative study with an analytic observational design and a cross-sectional approach, conducted at Panembahan Senopati Regional Hospital, Bantul, using secondary data from medical records. The population comprised 168 mothers with PROM, from which 63 respondents were selected by systematic random sampling based on inclusion and exclusion criteria. Data were analyzed univariately and bivariately using the Chi-Square test at a significance level of α = 0.05. The results showed that most respondents experienced term PROM (51 mothers; 81.0%), while preterm PROM occurred in 12 mothers (19.0%). Neonatal asphyxia was dominated by mild asphyxia (42 infants; 66.7%), followed by moderate asphyxia (16 infants; 25.4%), severe asphyxia (4 infants; 6.3%), and no asphyxia (1 infant; 1.6%). The Chi-Square test yielded p = 0.000 (p < 0.05), indicating a statistically significant relationship between premature rupture of membranes and the incidence of neonatal asphyxia. It can therefore be concluded that a significant relationship exists between premature rupture of membranes and neonatal asphyxia at Panembahan Senopati Regional Hospital, Bantul, in 2026. Early detection, close monitoring, and appropriate management of mothers with PROM must be continuously strengthened to reduce the risk of complications in newborns.

References

Abdella, S. H., Dadi, T. L., Lakew, A. M., Abdullahi, N. M., Yousuf, A. Y., & Younis, M. M. (2025). Birth asphyxia and its associated factors among newborns admitted to NICU in three public hospitals of Somali Region, Eastern Ethiopia. BMC Pediatrics, 25, Article 62. https://doi.org/10.1186/s12887-025-06249-5

Ali, R. N., Hiola, F. A. A., & Tomayahu, V. (2021). Faktor-faktor yang mempengaruhi kejadian komplikasi ketuban pecah dini (KPD) di RSUD Dr MM Dunda Limboto. Jurnal Health Sains, 2(3), 381-393. https://doi.org/10.46799/jhs.v2i3.130

Amin, N. F., Garancang, S., & Abunawas, K. (2023). Konsep umum populasi dan sampel dalam penelitian. Jurnal PILAR, 14(1). https://doi.org/10.26618/whw41w62

Anggriawan, A. (2025). Tinjauan klinis hypoxic-ischemic encephalopathy: Komplikasi neurologis asfiksia pada neonatus. Unpublished Clinical Review Manuscript.

Aprilliani, R., Ulfiana, E., & Ngadiyono, N. (2025). The correlations between premature rupture of membranes and gestational age with the incidence of asphyxia neonatorum. Jurnal Kebidanan, 11(2). https://doi.org/10.31983/jkb.v11i2.7552

Astuti. (2023). Faktor risiko usia ibu terhadap kejadian ketuban pecah dini. [Data sekunder tinjauan pustaka].

Ayu, B. F., & Syarif, S. (2021). Hubungan ketuban pecah dini dengan kejadian asfiksia neonatorum di RSUD H. Abdoel Madjid Batoe, Batang Hari, Jambi. [Laporan penelitian].

Badan Pusat Statistik. (2024, Februari 2). Mortality in Indonesia: The results of Population Census 2020 (Publikasi No. 04100.24002). Badan Pusat Statistik. https://www.bps.go.id

Chen, H., Hu, B., Lin, D., Xiu, Y., Ji, R., Zeng, H., & Wu, Y. (2024). Risk factors for premature rupture of membranes in pregnant women: a systematic review and meta-analysis. BMJ Open, 14, e077727. https://doi.org/10.1136/bmjopen-2024-077727

Cunningham, F. G., Leveno, K. J., Bloom, S. L., Dashe, J. S., Hoffman, B. L., Casey, B. M., & Spong, C. Y. (2022). Williams obstetrics (26th ed.). McGraw-Hill Education.

Dominguez, G. (2024). The care of preterm and term newborns with respiratory conditions: A systematic synthesis of evidence from low- and middle-income countries. Neonatology, 122(Suppl. 1). https://doi.org/10.1159/000542482

Ehrhardt, H., Aubert, M. A., Ådén, U., Draper, E. S., Gudmundsdottir, A., Varendi, H., Weber, T., Zemlin, M., Maier, R. F., & Zeitlin, J. (2023). Apgar scores and neurodevelopmental outcomes at 5 years of age in children born very preterm. Neonatology, 120(5), 612-621.

Erwina, et al. (2023). Faktor-faktor penyebab ketuban pecah dini. [Tinjauan pustaka penelitian].

Febrianti, A. Y., Sakinah, A. I., Setiawati, D., Jalaluddin, S., & Kara, S. A. (2025). Hubungan ketuban pecah dini dengan kejadian asfiksia neonatorum di RSIA Sitti Khadijah 1 Muhammadiyah Makassar. Ranah Research: Journal of Multidisciplinary Research and Development, 7(5), 3279-3284. https://doi.org/10.38035/rrj.v7i5

Hapsari, A., & Pratidina, W. G. (2025). Comprehensive review of meconium aspiration syndrome: Risk factors, complications, and treatment approaches. Medical and Health Journal, 4(2), 173-182. https://doi.org/10.20884/1.mhj.2025.4.2.14996

Kementerian Kesehatan Republik Indonesia. (2024). Profil Kesehatan Indonesia Tahun 2024. Kementerian Kesehatan RI. https://www.kemkes.go.id

Lestari, D. L. (2024). Asfiksia neonatorum. SCIENA, 3(1). e-ISSN 2810-0204.

Mardiyanti, L., & Hardiati, I. S. (2023). Hubungan ketuban pecah dini dengan kejadian asfiksia pada bayi baru lahir di ruang perinatologi RSUD Pademangan Jakarta tahun 2022. Jurnal Ilmiah Keperawatan, 9(3), 149-155. https://doi.org/10.33023/jikep.v9i3.1601

Noveldya, R. R., Lesnussa, F. N. T., & Mutika, W. T. (2025). Usia ibu dan paritas berhubungan dengan kejadian ketuban pecah dini. Jurnal Sains Kebidanan, 7(2), 64-71. https://doi.org/10.31983/jsk.v7i2.13447

Norazizah, Y., & Rahmawati, I. (2024). Hubungan ketuban pecah dini terhadap komplikasi pada bayi baru lahir di RSUD RA Kartini Jepara. Jurnal Kebidanan Universitas Al Hikmah Jepara, 2(2). ISSN 2985-5659.

Oetami, S., & Ambarwati, D. (2023). Gambaran kejadian ketuban pecah dini. Jurnal Bina Cipta Husada, 19(2), 22-31.

Palupi, J., & Maryanti, S. A. (2020). Resiko kejadian asfiksia neonatorum pada ketuban pecah dini. Jurnal MID-Z (Midwifery Zigot), 3(1). https://doi.org/10.36835/jurnalmidz.v3i1.638

Pemerintah Kabupaten Bantul. (2024). Rencana Kerja Pemerintah Daerah (RKPD) Kabupaten Bantul Tahun 2025. Pemerintah Kabupaten Bantul.

Perkumpulan Obstetri dan Ginekologi Indonesia (POGI). (2016). Pedoman Nasional Pelayanan Kedokteran: Ketuban Pecah Dini (KPD). POGI.

Robin, A., Tessier Doyen, N., Ben Rhaiem, S., Valette, N., Fermeaux, V., Preux, P.-M., et al. (2024). Influence of clinical risk factors for preterm premature rupture of membranes (PPROM) on the elastic strength of fetal membranes at term: a prospective study. PLoS ONE. https://doi.org/10.1371/journal.pone.0312760

Septyani, A., Astarie, A. D., & Lisca, S. M. (2025). Hubungan paritas dengan kejadian ketuban pecah dini. SIMFISIS Jurnal Kebidanan Indonesia, 2(3), 124. https://doi.org/10.53801/sjki.v2i3.124

Swarjana. (2024). Penelitian cross sectional: pengukuran variabel secara simultan. Edu Society: Jurnal Pendidikan, Ilmu Sosial, dan Pengabdian Kepada Masyarakat, 4(3), 1695-1708.

UNICEF. (n.d.). Neonatal mortality. UNICEF Data. https://data.unicef.org/topic/child-survival/neonatal-mortality/

World Health Organization. (2024, March 14). Newborn mortality. https://www.who.int/news-room/fact-sheets/detail/newborn-mortality

Downloads

Published

2026-09-07

Issue

Section

Artikel

How to Cite

Hubungan Ketuban Pecah Dini dengan Kejadian Asfiksia Neonatorum di RSUD Panembahan Senopati Bantul Tahun 2026. (2026). INOMATEC: Jurnal Inovasi Dan Kajian Multidisipliner Kontemporer , 1(11). https://portalpublikasi.com/index.php/inomatec/article/view/1613